REVIEW

Transpl. Int.

Achievements, Challenges and Promises of Minimally Invasive Liver Transplantation

  • 1. Hôpital Beaujon Service de Chirurgie Hépato-Pancréato-Biliaire & Transplantation Hépatique, Clichy, France

  • 2. Centre Hospitalier Universitaire Vaudois Service de chirurgie viscerale, Lausanne, Switzerland

The final, formatted version of the article will be published soon.

Abstract

The integration of minimal invasive (MIS) techniques in liver transplantation (LT) emerged as a natural progression following advances in laparoscopic and robotic hepato-pancreato-biliary surgery. However, it poses specific challenges that are inherent to LT. Chronologically, it is a recent topic that only emerged 2 decades ago in donors and recently in recipients, but it has showed a meteoric rise with tremendous progress over the last years. This review aimed to provide a comprehensive yet synthetic overview of the available data on minimal invasive liver transplantation (MILT), for both donor hepatectomy (DH), recipient hepatectomy and graft implantation. Developments were numerous: topnotch technical skills have not only been reported but have foremost been performed worldwide by an increasing number of groups. Technology also played a central role, as exemplified by the integration of 3D visualization techniques, the utilization of indocyanine green (ICG) near-infrared fluorescence camera system or the use of robotic technology. Research efforts finally illustrated this progress with a rapid rise of number of publications and adoption. The present analysis of the available data permitted to identify gaps that may be valuable to explore by future research projects.

Summary

Keywords

laparoscopy, minimal invasivesurgery, Minimally invasive liver transplantation, robotic, Transplant

Received

02 August 2025

Accepted

13 February 2026

Copyright

© 2026 Gomez, Labgaa, Karam, Dondero, Beghdadi, Hobeika, Dokmak and Lesurtel. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Mickaël Lesurtel, mickael.lesurtel@aphp.fr

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Outline

Share article