@ARTICLE{10.3389/ti.2022.10731, AUTHOR={Spaggiari, Mario and Petrochenkov, Egor and Patel, Hiteshi and Di Cocco, Pierpaolo and Almario-Alvarez, Jorge and Fratti, Alberto and Tzvetanov, Ivo and Benedetti, Enrico}, TITLE={Donor Size Doesn’t Impact En Bloc Kidney Transplant Outcomes: A Single-Center Experience and Review of Literature}, JOURNAL={Transplant International}, VOLUME={35}, YEAR={2022}, URL={https://www.frontierspartnerships.org/articles/10.3389/ti.2022.10731}, DOI={10.3389/ti.2022.10731}, ISSN={1432-2277}, ABSTRACT={Few transplant programs use kidneys from donors with body weight (BW)<10 kg due to higher incidence of vascular and urological complications, and DGF. The purpose of this study was to investigate the non-inferiority of pediatric en bloc kidneys from donors with BW<10 kg. We performed a single-center retrospective analysis of en bloc kidney transplants from pediatric donor cohort (n = 46) from 2003 to 2021 and stratified the outcomes by donor BW (small group, donor BW<10 kg, n = 30; standard group, donor BW<10 kg, n = 16). Graft function, rate of early post-transplant complications, graft and patient survival were analyzed. Complication rates were similar between both groups with 1 case of arterial thrombosis in the smaller group. Overall graft and patient survival rates were similar between the small and the standard group (graft survival—90% vs. 100%, p = 0.09; patient survival—96.7 vs. 100%, p = 0.48). Serum creatinine at 1, 3, 5 years was no different between groups. Reoperation rate was higher in the small group (23.3% vs. 6.25%, p = 0.03). The allograft from small donors could be related to higher reoperation rate in the early post-transplant period, but not associated with lower long-term graft and patient survival.} }