AUTHOR=Gultom Mitra , Rieben Robert 

TITLE=Complement, Coagulation, and Fibrinolysis: The Role of the Endothelium and Its Glycocalyx Layer in Xenotransplantation

JOURNAL=Transplant International

VOLUME=Volume 37 - 2024

YEAR=2024

URL=https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2024.13473

DOI=10.3389/ti.2024.13473

ISSN=1432-2277

ABSTRACT=Robert Rieben was born in Bern, Switzerland, where he also studied biology. During his PhD he worked on blood group ABO antibodies and, via contacts with Rafael Oriol and David Cooper, got in touch with xenotransplantation. As a postdoc in Mohammed Daha's lab in Leiden/NL, he started to work on the complement system and endothelial cells. At the same time, he collaborated in the first EU-funded xenotransplantation research projects 'Glycoimmunology', led by David Joziasse, and 'Xenotransplantation', led by Bo Samuelsson. Back in Switzerland, he started his own research group and continued to work on the concept of endothelial cell protection in xenotransplantation, allotransplantation, and ischemia/reperfusion injury. For the past 12 years, Robert Rieben has been aciliated to the German Transregio 127 research project on xenotransplantation, led by Bruno Reichart and Eckhard Wolf, and since 2020 he leads a Sinergia project of the Swiss National Science Foundation together with Joerg Seebach and Eckhard Wolf.