AUTHOR=Hoteit Mayssaa , Al-Masry Ahmad , Elbejjani Martine , Aoun Mabel , Abu-Dargham Rana , Medawar Walid , Abou Zeinab Hilal , Farhood Laila , Koubar Sahar H. 

TITLE=Sleepiness and Health-Related Quality of Life Among Kidney Transplant Recipients in a Low-Middle Income Country: A Cross-Sectional Study

JOURNAL=Transplant International

VOLUME=Volume 36 - 2023

YEAR=2023

URL=https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2023.11547

DOI=10.3389/ti.2023.11547

ISSN=1432-2277

ABSTRACT=This study aims to describe daytime sleepiness and health-related quality of life (HRQoL) among Lebanese kidney transplant (KT) recipients and to examine the medical, psychosocial and transplant factors related to them.

Methods:
This is a cross-sectional multi-center study involving KT recipients >18 years. Daytime sleepiness was assessed using ESS Questionnaire. HRQoL was measured using the SF-36 questionnaire. Social support was self-reported. A multivariable regression analysis evaluated factors associated with daytime sleepiness and HRQoL in our sample. 

Results:
118 patients were recruited over a two-year period. Excessive daytime sleepiness was prevalent in 12.7%. It was associated with Diabetes Mellitus (OR 4.11, 95%CI 0.96-17.63, P = 0.057) and obesity (OR 1.13, 95%CI 1.01, 1.27, P = 0.03). Social support and higher eGFR were associated with better scores on the MCS (β 24.13 P <0.01 and β 0.26 P <0.01) and the PCS (β 15.48 P <0.01 and β 0.22 P 0.02). Conversely, depression and hospitalization were negatively associated with the MCS (β -27.44, P<0.01 and β-9.87, P <0.01) and the PCS (β -0.28.49, P<0.01 and β -10.37, P< 0.01).

Conclusion:
Future research should provide in-depth insight into the interaction between these factors as well as between sleepiness and HRQoL among these patients.