AUTHOR=Anselmo Alessandro , Materazzo Marco , Di Lorenzo Nicola , Sensi Bruno , Riccetti Camilla , Lonardo Maria Teresa , Pellicciaro Marco , D’Amico Francesco , Siragusa Leandro , Tisone Giuseppe TITLE=Implementation of Blockchain Technology Could Increase Equity and Transparency in Organ Transplantation: A Narrative Review of an Emergent Tool JOURNAL=Transplant International VOLUME=Volume 36 - 2023 YEAR=2023 URL=https://www.frontierspartnerships.org/journals/transplant-international/articles/10.3389/ti.2023.10800 DOI=10.3389/ti.2023.10800 ISSN=1432-2277 ABSTRACT=In the last few years, innovative technology and health care digitalization played a major role in all medical fields and a great effort worldwide to manage this large amount of data, in terms of security and digital privacy has been made by different national health systems. Blockchain technology, a peer-to-peer distributed database without centralized authority, initially applied to Bitcoin protocol, soon gained popularity, thanks to its distributed immutable nature in several non-medical fields. Therefore, the aim of the present review (PROSPERO N° CRD42022316661) is to establish a putative future role of blockchain and distribution ledger technology (DLT) in the organ transplantation field and its role to overcome inequalities. Potential application of DLT in transplant encompasses preoperative assessment of the deceased donor, supranational crossover programs with the international waitlist databases. Despite preliminary DLT application could potentially reduce inequalities and discrimination thanks to its distributed, efficient, secure, trackable, and immutable nature.