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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">J. Abdom. Wall Surg.</journal-id>
<journal-title-group>
<journal-title>Journal of Abdominal Wall Surgery</journal-title>
<abbrev-journal-title abbrev-type="pubmed">J. Abdom. Wall Surg.</abbrev-journal-title>
</journal-title-group>
<issn pub-type="epub">2813-2092</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">17341</article-id>
<article-id pub-id-type="doi">10.3389/jaws.2026.17341</article-id>
<article-version article-version-type="Version of Record" vocab="NISO-RP-8-2008"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Case Report: Sequential posterior and anterior intraoperative fascial traction in extreme loss-of-domain incisional hernia</article-title>
<alt-title alt-title-type="left-running-head">Fortelny et al.</alt-title>
<alt-title alt-title-type="right-running-head">
<ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/jaws.2026.17341">10.3389/jaws.2026.17341</ext-link>
</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Fortelny</surname>
<given-names>Ren&#xe9; H.</given-names>
</name>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="corresp" rid="c001">&#x2a;</xref>
<uri xlink:href="https://loop.frontiersin.org/people/129086"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Froehlich</surname>
<given-names>Sandra</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kapitanov</surname>
<given-names>Teodor</given-names>
</name>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
<institution>Department of General, Visceral and Oncological Surgery, Sigmund Freud University Vienna</institution>, <city>Vienna</city>, <country country="AT">Austria</country>
</aff>
<aff id="aff2">
<label>2</label>
<institution>Wiener Gesundheitsverbund Klinik Floridsdorf</institution>, <city>Vienna</city>, <country country="AT">Austria</country>
</aff>
<author-notes>
<corresp id="c001">
<label>&#x2a;</label>Correspondence: Ren&#xe9; H. Fortelny, <email xlink:href="mailto:dr.fortelny@gmail.com">dr.fortelny@gmail.com</email>
</corresp>
</author-notes>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-11-13">
<day>13</day>
<month>11</month>
<year>2026</year>
</pub-date>
<pub-date publication-format="electronic" date-type="collection">
<year>2026</year>
</pub-date>
<volume>5</volume>
<elocation-id>17341</elocation-id>
<history>
<date date-type="received">
<day>09</day>
<month>07</month>
<year>2026</year>
</date>
<date date-type="rev-recd">
<day>25</day>
<month>10</month>
<year>2026</year>
</date>
<date date-type="accepted">
<day>04</day>
<month>11</month>
<year>2026</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#xa9; 2026 Fortelny, Froehlich and Kapitanov.</copyright-statement>
<copyright-year>2026</copyright-year>
<copyright-holder>Fortelny, Froehlich and Kapitanov</copyright-holder>
<license>
<ali:license_ref start_date="2026-11-13">https://creativecommons.org/licenses/by/4.0/</ali:license_ref>
<license-p>This is an open-access article distributed under the terms of the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License (CC BY)</ext-link>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</license-p>
</license>
</permissions>
<abstract>
<sec>
<title>Background</title>
<p>Incisional hernias with loss of domain (LOD) following open abdomen management, visceral surgery, and cutaneous grafting present an extreme reconstructive challenge. Intraoperative fascial traction (IFT) using the Fasciotens&#xae; Abdomen device has been established as an effective adjunct to reduce fascial gaps in large ventral hernias (EHS W3). Conventional application targets the anterior rectus sheath. We describe a sequential double-layer IFT approach, first applied to the posterior and then to the anterior layer, in an extreme LOD case, and report whether posterior-layer traction allowed closure of the posterior layer without a bridging mesh.</p>
</sec>
<sec>
<title>Case Presentation</title>
<p>A 35-year-old male (BMI 24, DM II, nicotine abuse, polytoxicomania) presented with a massive LOD incisional hernia following polytrauma (2011) with right nephrectomy, transverse colon resection, colostomy/ileostomy, open abdomen, split-skin grafting, and a prior failed IPOM bridging repair (2021). After multimodal prehabilitation (weight reduction, drug detoxification, partial tissue expansion, and botulinum toxin A [BTA] 8 weeks preoperatively), definitive reconstruction was performed in March 2025 using a combined Rives&#x2013;Stoppa/Madrid/bilateral TAR approach. IFT applied to the posterior layer for 30&#xa0;min (up to 18&#xa0;kg) allowed closure of this layer from the caudal margin to the umbilicus, but not in the cranial segment, where peritoneum was absent after open abdomen management and skin grafting; a bridging mesh, OviTex&#xae; S2 (30 &#xd7; 25&#xa0;cm, &#x2265;5&#xa0;cm overlap), was therefore placed cranially as a visceral separation layer. A second IFT phase targeting the anterior sheath (30&#xa0;min) then allowed primary closure of the remaining 10-cm anterior defect. A retromuscular mesh DynaMesh&#xae;-CICAT (30 &#xd7; 35&#xa0;cm) was placed, and the linea alba was reconstructed using the small-bites technique (Monomax 2.0). A seroma at 6 months was aspirated once (400&#xa0;mL, sterile); CT at 12 months confirmed no recurrence.</p>
</sec>
<sec>
<title>Discussion</title>
<p>To our knowledge, this is the first reported case of sequential posterior&#x2013;anterior IFT using the Fasciotens&#xae; device. Posterior-layer traction allowed closure of the caudal posterior layer but did not avoid a bridging mesh in the cranial segment. After anterior IFT, the anterior fascia was closed primarily. Whether posterior IFT reduces the bridged area cannot be determined from a single case.</p>
</sec>
</abstract>
<kwd-group>
<kwd>case report</kwd>
<kwd>Fasciotens<sup>&#xae;</sup>
</kwd>
<kwd>incisional hernia</kwd>
<kwd>intraoperative fascial traction</kwd>
<kwd>loss of domain</kwd>
</kwd-group>
<funding-group>
<funding-statement>The author(s) declared that financial support was not received for this work and/or its publication.</funding-statement>
</funding-group>
<counts>
<fig-count count="4"/>
<table-count count="0"/>
<equation-count count="0"/>
<ref-count count="24"/>
<page-count count="8"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>Incisional hernias with loss of domain (LOD) rank among the most complex problems in abdominal wall surgery. In these patients, herniated viscera occupy a substantial proportion of the abdominal volume, rendering simple reduction and fascial closure impossible without significant risk of abdominal compartment syndrome (ACS) [<xref ref-type="bibr" rid="B1">1</xref>]. This challenge is amplified when LOD results from multiple prior abdominal emergencies, open abdomen management, visceral organ resections, and cutaneous reconstruction, which collectively destroy normal tissue planes, eliminate peritoneum, and produce severe myofascial retraction.</p>
<p>Current strategies to achieve fascial closure in LOD hernias include preoperative botulinum toxin A (BTA) injection into the lateral abdominal wall muscles, progressive preoperative pneumoperitoneum (PPP), and intraoperative component separation techniques (CST)&#x2014;specifically anterior component separation (ACS) and posterior component separation with transversus abdominis release (TAR/PCS-TAR) [<xref ref-type="bibr" rid="B2">2</xref>&#x2013;<xref ref-type="bibr" rid="B6">6</xref>]. Each approach extends the reach of fascial closure but carries its own complication profile and technical complexity.</p>
<p>The concept of intraoperative fascial traction was first introduced by Eucker et al., who used a self-built abdominal wall expander system (AWEX) to achieve primary fascial closure in giant incisional hernias and grafted laparostomata without lateral release [<xref ref-type="bibr" rid="B7">7</xref>]. Intraoperative fascial traction (IFT) using the Fasciotens&#xae; Abdomen device (Thoennessen Medical Devices, Germany) has emerged as an additional tool within this armamentarium. The device exerts a controlled diagonal-anterior traction force on the rectus sheath edges, inducing viscoelastic creep of the fascial tissue and reducing the fascial gap by a mean of 9&#x2013;10&#xa0;cm after 30&#x2013;35&#xa0;min of application [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>]. Published series have demonstrated primary closure rates of 90%&#x2013;97% when IFT is combined with BTA and, where required, CST [<xref ref-type="bibr" rid="B10">10</xref>]. Conventionally, Fasciotens&#xae; traction is applied to the anterior rectus sheath.</p>
<p>We report an extreme LOD case in which the posterior layer could not be closed after bilateral TAR. IFT was therefore first applied to the posterior layer, to examine whether traction would allow closure of this layer without a bridging mesh, and then, after posterior reconstruction, to the anterior rectus sheath. To our knowledge, this sequential application has not been described before.</p>
</sec>
<sec id="s2">
<title>Case presentation</title>
<sec id="s2-1">
<title>Patient history and comorbidities</title>
<p>A 35-year-old male (BMI 24&#xa0;kg/m<sup>2</sup>) with diabetes mellitus type II, hyperlipidaemia, nicotine abuse (30 cigarettes/day; nicotine abstinence was achieved before definitive reconstruction), and polytoxicomania (on substitution with Compensan&#xae; and high-dose Seroquel&#xae;) presented to our unit. In March 2011, he had suffered severe polytrauma following a fall before a subway train. Injuries included pelvic ring fracture, multiple extremity fractures, post-traumatic plexus paresis of the lower extremities (left &#x3e; right), haemothorax with serial rib fractures (right), bladder rupture, and right kidney rupture requiring nephrectomy. Concurrent abdominal injuries comprised splenic rupture (managed non-operatively) and rupture of the transverse colon, necessitating right hemicolectomy with end colostomy and ileostomy. Abdominal wound closure was achieved with a skin flap closure.</p>
<p>In June 2021, the patient was admitted with an acute abdomen caused by an incarcerated incisional hernia with small bowel gangrene. Emergency surgery included para-ileostomy management, ileo-transversostomy, and open abdomen (OA) treatment with vacuum-assisted closure (VAC). An intraperitoneal onlay mesh (IPOM) bridging repair was performed using a biological mesh. The subsequent course required mesh explantation due to infection. Final wound closure was achieved with split-skin grafting, leaving a large epigastric segment without peritoneal coverage.</p>
<sec id="s2-1-1">
<title>Family history</title>
<p>Non-contributory. The loss of domain in this patient resulted from post-traumatic and postsurgical sequelae (polytrauma with visceral organ resection, subsequent open abdomen management, and recurrent incisional hernia) rather than from a hereditary connective tissue disorder or familial hernia predisposition.</p>
</sec>
<sec id="s2-1-2">
<title>Clinical findings</title>
<p>On repeated preoperative examination, the patient had recurrent superficial wound breakdown at the margin between native skin and the split-skin-grafted hernia sac segment; these lesions were managed conservatively with local wound therapy (hypochlorous acid solution, Granudacyn&#xae;) and healed on each occasion prior to definitive reconstruction. According to the EHS classification, the hernia was a recurrent midline incisional hernia, M1&#x2013;M4, W3, with a maximum preoperative defect width of 21&#xa0;cm [<xref ref-type="bibr" rid="B11">11</xref>].</p>
</sec>
</sec>
<sec id="s2-2">
<title>Prehabilitation</title>
<p>Given the extreme complexity of this case, a structured prehabilitation program was initiated [<xref ref-type="bibr" rid="B12">12</xref>]. This included targeted weight reduction, a supervised drug substitution program and placement of subcutaneous tissue expanders to allow uncomplicated skin closure at the definitive repair, because the split-skin graft could not be preserved. In June 2024, four expanders were implanted (Polytech; one 800&#xa0;mL expander with integrated valve in the right precostal position, and two 340&#xa0;mL expanders with integrated valve and one 320&#xa0;mL expander with remote valve in the right and left lower abdomen). In December 2024, an infected expander was removed from the left lower abdomen. The expanders were filled with a total of 5&#xa0;L over 6 weeks. In total, three expanders required explantation because of infection of the implant pocket with <italic>Staphylococcus</italic> epidermidis, which could not be controlled by systemic cephalosporin therapy according to the antibiogram; the 800&#xa0;mL precostal expander on the right remained <italic>in situ</italic> until definitive surgery. Eight weeks preoperatively, BTA (Botox&#xae;, Allergan/AbbVie, Irvine, CA, USA; 150 U per side; 300 U total) was injected bilaterally under ultrasound guidance into all three lateral abdominal wall muscles (external oblique, internal oblique, and transversus abdominis) to induce chemical myorelaxation and partial restoration of abdominal domain [<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>]. This 8-week interval exceeded the conventional 2&#x2013;4-week window used in most preoperative BTA protocols [<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>], but remained within the reported duration of botulinum toxin-induced relaxation and allowed additional time for concurrent tissue-expander management and multimodal optimisation before definitive reconstruction.</p>
<p>Preoperative CT volumetry quantified the extent of loss of domain (<xref ref-type="fig" rid="F1">Figure 1</xref>). Hernia sac volume (HSV) was calculated using the ellipsoid formula (&#x3c0;/6 &#xd7; cranio-caudal &#xd7; transversal &#xd7; anterior-posterior) from axial and sagittal CT sections: HSV &#x3d; &#x3c0;/6 &#xd7; 28.0 &#xd7; 20.6 &#xd7; 22.0&#xa0;cm &#x3d; 6,644&#xa0;mL. Abdominal cavity volume (ACV) was determined analogously: ACV &#x3d; &#x3c0;/6 &#xd7; 30.0 &#xd7; 32.0 &#xd7; 20.0&#xa0;cm &#x3d; 10,053&#xa0;mL. The Tanaka Index (HSV/ACV) was 0.661 (threshold &#x2265;0.25; 2.6-fold above the LOD threshold) and the Sabbagh Index (HSV/[HSV &#x2b; ACV] &#xd7; 100%) was 39.8% (threshold &#x2265;20%), confirming extreme LOD by both validated CT volumetry criteria [<xref ref-type="bibr" rid="B1">1</xref>, <xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>]. These indices underscored the necessity of maximal multimodal reconstruction.</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption>
<p>Clinical presentation and CT scan.</p>
</caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="jaws-05-17341-g001.tif">
<alt-text content-type="machine-generated">Two photographs on the left display a person with significant abdominal skin laxity and an overhanging abdominal mass. Four adjacent CT scan images show cross-sectional and coronal views of the lower abdomen and pelvis, highlighting the soft tissue distribution and anatomical structures for medical evaluation.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s2-3">
<title>Operative technique (March 2025)</title>
<p>The patient was positioned supine under general anaesthesia. Intraoperative intra-abdominal pressure (IAP) was measured throughout the procedure via bladder catheter.</p>
<p>The procedure began with explantation of the remaining tissue expander and removal of the split-skin graft, followed by extensive adhesiolysis of the small bowel. The retromuscular plane was developed using the Rives&#x2013;Stoppa technique in the cranial portion of the defect [<xref ref-type="bibr" rid="B15">15</xref>], including pre-transversalis and pre-diaphragmatic dissection according to the Madrid modification [<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. Bilateral TAR was performed from cranial to caudal to maximise myofascial advancement [<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>, <xref ref-type="bibr" rid="B18">18</xref>].</p>
<p>Fascial defect width was not measured at every stage. The maximum preoperative defect width was 21&#xa0;cm. According to the operative report, posterior IFT allowed approximation of the posterior layer from the symphysis to the umbilicus, after which an anterior fascial defect of 10&#xa0;cm remained; after anterior IFT, the anterior fascia was closed primarily. The width of the posterior-layer defect after TAR and before posterior traction was not recorded.</p>
<p>Due to the absence of peritoneum in the upper abdominal segment (consequence of the prior open abdomen and split-skin grafting), primary closure of the posterior layer was not achievable throughout the entire defect. The following sequential IFT strategy was therefore employed:<list list-type="simple">
<list-item>
<p>Step 1 &#x2013; Posterior layer IFT: The Fasciotens&#xae; Abdomen device was applied to the edges of the posterior layer (<xref ref-type="fig" rid="F2">Figure 2A</xref>). The traction sutures engaged the posterior rectus sheath from the caudal end of the defect to 8&#xa0;cm below the xiphoid; cranial to this level, the posterior rectus sheath was kept intact according to the Madrid technique [<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. No hernia sac tissue was present, because the entire area of exposed intestine had previously been covered with a split-skin graft. A controlled traction force of up to 18&#xa0;kg was maintained for 30&#xa0;min. This reduced the posterior fascial gap sufficiently to allow closure of the posterior layer from the caudal wound margin to the umbilicus (<xref ref-type="fig" rid="F2">Figure 2B</xref>), but not in the cranial segment.</p>
</list-item>
<list-item>
<p>Step 2 &#x2013; Cranial posterior bridging mesh reinforcement: In the epigastric segment, where the posterior sheath was absent, a posterior bridging mesh (visceral separation layer) was placed using OviTex&#xae; S2 (OviTex&#xae; 1S Permanent Reinforced Tissue Matrix, Aroa Biosurgery/Tela Bio; 30 &#xd7; 25&#xa0;cm) with an overlap of at least 5&#xa0;cm [<xref ref-type="bibr" rid="B19">19</xref>]. The mesh was secured with a running suture to the borders of the posterior sheath caudally and to the diaphragmatic crura cranially (<xref ref-type="fig" rid="F2">Figure 2C</xref>).</p>
</list-item>
<list-item>
<p>Step 3 &#x2013; Anterior sheath IFT: The Fasciotens&#xae; device was repositioned and applied to the edges of the anterior rectus sheath for a further 30&#xa0;min at a traction force of up to 18&#xa0;kg, to address the remaining anterior defect of 10&#xa0;cm. Following fascial creep, primary closure of the anterior fascia was achieved (<xref ref-type="fig" rid="F2">Figure 2D</xref>).</p>
</list-item>
<list-item>
<p>Step 4 &#x2013; Retromuscular mesh: A DynaMesh&#xae;-CICAT mesh (30 &#xd7; 35&#xa0;cm; PVDF monofilament; FEG Textiltechnik, Aachen, Germany) was placed in the retrorectus/retromuscular position to reinforce the repair (<xref ref-type="fig" rid="F3">Figure 3</xref>).</p>
</list-item>
<list-item>
<p>Step 5 &#x2013; Linea alba closure: The midline was closed using the small-bites technique with Monomax&#xae; 2.0 monofilament suture (B. Braun Surgical, Melsungen, Germany), as recommended for primary fascial closure to reduce wound healing complications (<xref ref-type="fig" rid="F3">Figure 3</xref>) [<xref ref-type="bibr" rid="B20">20</xref>&#x2013;<xref ref-type="bibr" rid="B22">22</xref>].</p>
</list-item>
<list-item>
<p>Step 6 &#x2013; Wound management: After skin excision of the prior graft area, wound closure was reinforced with negative pressure wound therapy (NPWT) applied to the closed incision [<xref ref-type="bibr" rid="B23">23</xref>].</p>
</list-item>
</list>
</p>
<fig id="F2" position="float">
<label>FIGURE 2</label>
<caption>
<p>Schematic representation of sequential double-layer intraoperative fascial traction (IFT): <bold>(A)</bold> First IFT phase: IFT device applied to the posterior rectus sheath edge. <bold>(B)</bold> Caudal-to-umbilical posterior sheath closure by small bites technique. <bold>(C)</bold> Posterior bridging mesh (OviTex&#xae; S2) 30 &#xd7; 25&#xa0;cm implantation. <bold>(D)</bold> Second IFT phase: IFT device repositioned to the anterior rectus sheath.</p>
</caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="jaws-05-17341-g002.tif">
<alt-text content-type="machine-generated">Panel A shows surgeons using a large surgical closure device during an abdominal wall reconstruction, with sutures in place. Panel B displays gloved hands adjusting tissues in an open abdominal cavity. Panel C presents a close-up of the abdominal wall repair with visible sutures and mesh. Panel D features surgeons operating the closure device over the reconstructed abdominal wall.</alt-text>
</graphic>
</fig>
<fig id="F3" position="float">
<label>FIGURE 3</label>
<caption>
<p>Retromuscular mesh (DynaMesh&#xae;-CICAT) 30 &#xd7; 35&#xa0;cm placement and complete midline closure in small bites.</p>
</caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="jaws-05-17341-g003.tif">
<alt-text content-type="machine-generated">Surgical procedure showing abdominal wall reconstruction. Left panel: exposed tissue and muscle with visible mesh implant and surgical instruments holding sutures in place. Right panel: surgeon&#x27;s gloved hand using forceps to close the surgical incision.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s2-4">
<title>Postoperative course and follow-up</title>
<sec id="s2-4-1">
<title>Clinician-assessed outcomes</title>
<p>The patient was extubated 24&#xa0;h after surgery and stayed 2&#xa0;days in the intermediate care unit. IAP remained below 12&#xa0;mmHg during the 48&#xa0;h of postoperative monitoring, with no signs of abdominal compartment syndrome. NPWT was removed on postoperative day 4, and the wound healed primarily. The patient was discharged on postoperative day 10. The only complication was a seroma requiring a single percutaneous aspiration (see below; Clavien&#x2013;Dindo grade I). There was no readmission and no reoperation. Follow-up visits took place at 14 days and at 3, 6 and 12 months, with CT at 6 and 12 months. At 12 months, the abdominal wall was clinically stable without palpable recurrence, with a cosmetically acceptable result (<xref ref-type="fig" rid="F4">Figure 4</xref>).</p>
<fig id="F4" position="float">
<label>FIGURE 4</label>
<caption>
<p>12-month postop. Clinical presentation and CT scan.</p>
</caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="jaws-05-17341-g004.tif">
<alt-text content-type="machine-generated">Close-up and side views of an adult torso exhibiting significant surgical scarring and loose, excess abdominal skin, accompanied by four black-and-white cross-sectional CT scans displaying varying levels of abdominal soft tissue and internal organs.</alt-text>
</graphic>
</fig>
</sec>
<sec id="s2-4-2">
<title>Important follow-up results</title>
<p>CT at 6 months showed a seroma 1.5&#xa0;cm thick and 20&#xa0;cm in diameter, which was aspirated percutaneously on 27 October 2025 (400&#xa0;mL); the culture showed no bacterial growth. CT at 12 months (30 April 2026) showed an intact reconstruction without recurrent incisional hernia, mesh migration or residual seroma (<xref ref-type="fig" rid="F4">Figure 4</xref>).</p>
</sec>
<sec id="s2-4-3">
<title>Patient-assessed outcomes</title>
<p>The patient reported resolution of chronic back pain, improved mobility and the ability to sit for prolonged periods (see 3.1 Patient perspective). No validated quality-of-life instrument (e.g., SF-36) was used; the patient confirmed his satisfaction with the result, in particular the marked improvement in mobility.</p>
</sec>
<sec id="s2-4-4">
<title>Adherence and tolerability</title>
<p>BTA injection was well tolerated without adverse effects. The patient continued the substitution programme and maintained nicotine abstinence after surgery. An abdominal binder was worn for 4 weeks.</p>
</sec>
<sec id="s2-4-5">
<title>Adverse and unanticipated events</title>
<p>During prehabilitation, three tissue expanders had to be removed because of infection, and recurrent superficial wound breakdown at the margin of the skin graft was managed conservatively. No intraoperative complications occurred. Apart from the seroma described above, no postoperative adverse or unanticipated events occurred.</p>
</sec>
</sec>
</sec>
<sec sec-type="discussion" id="s3">
<title>Discussion</title>
<p>This case report documents an extreme LOD incisional hernia resulting from a cascade of abdominal catastrophes spanning 14 years&#x2014;polytrauma, emergency visceral surgery, open abdomen, skin grafting, and repeated hernia repair failure. The final operative solution required the integration of multiple contemporary techniques, including BTA prehabilitation, the Rives&#x2013;Stoppa procedure, the Madrid modification of posterior component separation, bilateral TAR, and IFT with Fasciotens&#xae;.</p>
<p>The defining innovation of this case was the sequential application of IFT at two distinct fascial layers. IFT with the Fasciotens&#xae; Abdomen device exploits the viscoelastic properties of fascial tissue. When a sustained, measured traction force (&#x2265;10&#xa0;kg for 30&#x2013;35&#xa0;min) is applied, the fascial matrix undergoes stress relaxation and creep, resulting in permanent elongation of the sheet without structural disruption [<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>]. All published series to date have applied this principle exclusively to the anterior rectus sheath, where the traction arms grip the fascial edge and pull anteriorly and diagonally. The single earlier report in which the device engaged the posterior fascial plane at all was an open-abdomen case, in which a mesh bridging both the posterior and anterior fascia was traction-loaded as one combined unit rather than through two discrete, layer-specific applications [<xref ref-type="bibr" rid="B24">24</xref>]. Independent, staged traction of the posterior sheath as a distinct intraoperative step, as performed in the present case, has, to our knowledge, not been previously described.</p>
<p>In the present case, the standard anatomy was profoundly altered. Bilateral TAR alone was insufficient to close the posterior layer across the entire defect length because the severe lateral muscle retraction after years of OA management had reduced the effective myofascial length. After 30&#xa0;min of posterior IFT, the posterior layer could be closed from the caudal wound margin to the umbilicus. Posterior IFT did not, however, achieve closure of the posterior layer without bridging: in the cranial segment, a bridging mesh of OviTex&#xae; S2 (&#x2265;5&#xa0;cm overlap) was still required to provide visceral separation. In this segment, the limiting factor was not only the width of the gap but the absence of peritoneum and posterior sheath after OA management and skin grafting, a tissue deficit that traction cannot replace. Because the width of the posterior-layer defect before traction was not recorded, it cannot be determined how much posterior IFT reduced the extent of the bridged area. The present case therefore shows that posterior IFT is feasible, but not that it avoids bridging of the posterior layer.</p>
<p>The second IFT phase, targeting the anterior sheath, then addressed the remaining fascial gap at the outer layer. This sequential strategy is conceptually analogous to the layered closure principle in complex wound management: each layer is mobilised and closed independently before the next is addressed. Conventional traction on the anterior rectus sheath alone did not appear feasible because of the size of the defect, even after bilateral TAR. IFT was therefore first applied to the posterior layer and, after successful approximation of this layer from the symphysis to the umbilicus, to the anterior sheath, where a defect of 10&#xa0;cm remained. In addition, after Rives&#x2013;Stoppa dissection and TAR the two layers are separated, so that traction on the anterior sheath does not approximate the posterior layer, and the posterior layer had to be closed and the cranial bridge placed before the retromuscular mesh could be positioned. Whether separate phases offer a mechanical advantage over simultaneous traction cannot be judged from a single case.</p>
<p>In published series, IFT reduced the fascial gap by a mean of about 10&#xa0;cm and allowed closure in 90% of W3 hernias; combined with BTA, additional TAR was required in 30% of patients [<xref ref-type="bibr" rid="B9">9</xref>, <xref ref-type="bibr" rid="B10">10</xref>]. The present case differed from these series by the loss of peritoneum in the cranial segment, multi-plane adhesions and previous biological mesh explantation. Preoperative BTA reduces the need for component separation in large incisional hernias [<xref ref-type="bibr" rid="B5">5</xref>, <xref ref-type="bibr" rid="B6">6</xref>]. In this patient, BTA was one element of the multimodal preparation; its individual contribution cannot be determined from a single case.</p>
<p>The Madrid modification of PCS-TAR used in the subxiphoid portion of this case extends the standard retrorectus plane by preserving the posterior sheath intact and developing a preperitoneal dissection anterior to the transversalis fascia, including pre-diaphragmatic dissection for subdiaphragmatic defects [<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>]. This approach is essential when the cranial extent of the defect approaches or involves the xiphoid, as in the present case, providing the space necessary for adequate mesh overlap at the superior border.</p>
<p>IAP monitoring throughout the procedure and for 48 postoperative hours was critical. Restoration of abdominal domain in LOD hernias carries an inherent risk of raised IAP and ACS. IAP remained within safe limits in our patient, consistent with the thorough preoperative preparation and the incremental nature of the reconstruction. The Tanaka Index, computed from preoperative CT, provides a validated quantitative measure of domain loss and may guide selection of preoperative optimisation intensity [<xref ref-type="bibr" rid="B1">1</xref>]. Preoperative CT volumetry in our patient (Tanaka Index 0.661, Sabbagh Index 39.8%; see section <italic>Prehabilitation</italic>) confirmed extreme LOD and justified the maximal multimodal strategy [<xref ref-type="bibr" rid="B13">13</xref>, <xref ref-type="bibr" rid="B14">14</xref>].</p>
<p>The choice of OviTex&#xae; S2 for the cranial posterior bridging mesh segment reflects the need for a biologically compatible, reinforced tissue matrix in a contaminated-adjacent field with no native peritoneum. Biologic or biocomposite meshes are preferred in such reconstructions to reduce the risk of mesh infection and to allow tissue ingrowth in the absence of a peritoneal layer [<xref ref-type="bibr" rid="B19">19</xref>].</p>
<p>The infection of three tissue expanders during prehabilitation raised the risk of mesh infection at the definitive repair. The implant-pocket infections (<italic>Staphylococcus</italic> epidermidis) could not be controlled by systemic cephalosporin therapy according to the antibiogram and required explantation of the affected expanders. Reconstruction was performed 4&#xa0;weeks after the last explantation, once the infection had resolved. The remaining expander was removed at the beginning of the operation and its capsule excised; because there were no signs of infection, no swabs were taken. A macroporous PVDF mesh was placed in the retromuscular position, and a reinforced tissue matrix was chosen for the cranial posterior bridge. No mesh-related infection occurred during 12 months of follow-up, and the aspirated seroma was sterile. Nevertheless, infected expanders should be regarded as a risk factor for mesh infection, and their role in prehabilitation for LOD hernia repair should be weighed against this risk.</p>
<sec id="s3-1">
<title>Strengths and limitations</title>
<p>This report documents abdominal wall reconstruction in a patient with extreme loss of domain (Tanaka Index 0.661), a previous failed repair and severely altered tissue planes after open abdomen management and split-skin grafting. Its strengths are the description of a layer-specific, sequential application of IFT to the posterior and then the anterior layer, which extends the technique beyond conventional anterior-layer traction; the quantitative characterisation of loss of domain by preoperative CT volumetry; the stepwise operative description with photographs; perioperative IAP monitoring; clinical and CT follow-up at 12 months; and the patient&#x2019;s perspective on functional outcome. The limitations are those of a single case. Generalisability is restricted, and whether the outcome reflects the dual-layer technique itself, the combination with BTA or the extensive TAR dissection cannot be determined. Posterior IFT did not avoid a bridging mesh in the cranial segment. Fascial defect width was not measured at every stage: the maximum preoperative width (21&#xa0;cm) and the residual anterior defect before anterior traction (10&#xa0;cm) are reported, but the width of the posterior-layer defect before and after posterior traction was not recorded; the additional approximation achieved by posterior traction, and whether it reduced the extent of cranial bridging, therefore cannot be quantified. Intra-abdominal and plateau airway pressures before and after fascial closure were not documented, so the physiological effect of restoring the abdominal domain cannot be quantified. Future reports of sequential IFT should measure the width and length of the fascial gap at each phase and the traction force applied. No validated quality-of-life instrument was used. Finally, smoking cessation in this patient with previous heavy nicotine use (30 cigarettes/day) was not supported by a structured smoking-cessation programme.</p>
</sec>
<sec id="s3-2">
<title>Patient perspective</title>
<p>Before surgery, the patient had lost hope that his condition could improve. Postoperatively, he describes himself as immensely grateful, reporting a markedly better quality of life: his chronic back pain has resolved, and despite his pre-existing lower-limb impairment he can now move considerably more freely and sit for prolonged periods without difficulty. These functional gains have made vocational retraining feasible, with eventual reintegration into the workforce anticipated, and he is due to be married in the near future. In his own words, a new chapter of his life has begun.</p>
</sec>
</sec>
<sec sec-type="conclusion" id="s4">
<title>Conclusion</title>
<p>Sequential posterior and anterior intraoperative fascial traction with the Fasciotens&#xae; Abdomen device was feasible in this case of extreme LOD. Posterior IFT allowed closure of the posterior layer from the caudal margin to the umbilicus, but did not avoid a bridging mesh in the cranial segment, where peritoneum was absent. After anterior IFT, the anterior fascia was closed primarily, and the reconstruction remained intact at 12 months. This single case therefore does not show that posterior IFT can replace bridging of the posterior layer. Prospective series with measurement of the fascial gap at each phase are needed to determine whether posterior IFT reduces the extent of bridging and in which patients it allows complete posterior closure.</p>
</sec>
</body>
<back>
<sec sec-type="data-availability" id="s5">
<title>Data availability statement</title>
<p>The original contributions presented in the study are included in the article/<xref ref-type="sec" rid="s12">Supplementary Material</xref>, further inquiries can be directed to the corresponding author.</p>
</sec>
<sec sec-type="ethics-statement" id="s6">
<title>Ethics statement</title>
<p>The studies involving humans were approved by Wiener Gesundheitsverbund, Ethikkommission. The studies were conducted in accordance with the local legislation and institutional requirements. The ethics committee/institutional review board waived the requirement of written informed consent for participation from the participants or the participants&#x2019; legal guardians/next of kin because only case report, no ethical vote necessary. Written informed consent was obtained from the individual for the publication of any potentially identifiable images or data included in this article.</p>
</sec>
<sec sec-type="author-contributions" id="s7">
<title>Author contributions</title>
<p>RF: conception, surgical technique, manuscript drafting and revision. SF and TK: manuscript drafting and revision. All authors contributed to the article and approved the submitted version.</p>
</sec>
<sec sec-type="COI-statement" id="s9">
<title>Conflict of interest</title>
<p>The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="ai-statement" id="s10">
<title>Generative AI statement</title>
<p>The author(s) declared that generative AI was not used in the creation of this manuscript.</p>
<p>Any alternative text (alt text) provided alongside figures in this article has been generated by Frontiers with the support of artificial intelligence and reasonable efforts have been made to ensure accuracy, including review by the authors wherever possible. If you identify any issues, please contact us.</p>
</sec>
<sec sec-type="disclaimer" id="s11">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec sec-type="supplementary-material" id="s12">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontierspartnerships.org/articles/10.3389/jaws.2026.17341/full#supplementary-material">https://www.frontierspartnerships.org/articles/10.3389/jaws.2026.17341/full&#x23;supplementary-material</ext-link>
</p>
<supplementary-material xlink:href="Supplementaryfile1.docx" id="SM1" mimetype="application/docx" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
<ref-list>
<title>References</title>
<ref id="B1">
<label>1.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Girieasen</surname>
<given-names>MS</given-names>
</name>
<name>
<surname>Lakshmanan</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Farook</surname>
<given-names>M</given-names>
</name>
</person-group>. <article-title>A preoperative algorithm for loss of domain hernia repair: stratified management using the Tanaka index in 50 cases</article-title>. <source>J Abdom Wall Surg</source> (<year>2025</year>) <volume>4</volume>:<fpage>14769</fpage>. <pub-id pub-id-type="doi">10.3389/jaws.2025.14769</pub-id>
</mixed-citation>
</ref>
<ref id="B2">
<label>2.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Eucker</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Rosenberg</surname>
<given-names>R</given-names>
</name>
</person-group>. <article-title>Loss of domain and reduction in median suture tension</article-title>. <source>Chirurgie (Heidelb)</source> (<year>2024</year>) <volume>95</volume>(<issue>1</issue>):<fpage>34</fpage>&#x2013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1007/s00104-023-01997-5</pub-id>
</mixed-citation>
</ref>
<ref id="B3">
<label>3.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Mohamedahmed</surname>
<given-names>AY</given-names>
</name>
<name>
<surname>Issa</surname>
<given-names>MT</given-names>
</name>
<name>
<surname>Zaman</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Mohammed</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Mohamedahmed</surname>
<given-names>MY</given-names>
</name>
<name>
<surname>Hamid</surname>
<given-names>M</given-names>
</name>
<etal/>
</person-group> <article-title>Outcomes of anterior component separation <italic>versus</italic> posterior component separation with transversus abdominis muscle release for large incisional hernias: a systematic review and meta-analysis</article-title>. <source>Hernia</source> (<year>2025</year>) <volume>29</volume>(<issue>1</issue>):<fpage>289</fpage>. <pub-id pub-id-type="doi">10.1007/s10029-025-03487-5</pub-id>
</mixed-citation>
</ref>
<ref id="B4">
<label>4.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Marte</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Tufo</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Ferronetti</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Di Maio</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Russo</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Sordelli</surname>
<given-names>IF</given-names>
</name>
<etal/>
</person-group> <article-title>Posterior component separation with TAR: lessons learned from our first consecutive 52 cases</article-title>. <source>Updates Surg</source> (<year>2023</year>) <volume>75</volume>(<issue>3</issue>):<fpage>723</fpage>&#x2013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1007/s13304-022-01418-y</pub-id>
</mixed-citation>
</ref>
<ref id="B5">
<label>5.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Bueno-Lled&#xf3;</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Carre&#xf1;o-Saenz</surname>
<given-names>O</given-names>
</name>
<name>
<surname>Torregrosa-Gallud</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Pous-Serrano</surname>
<given-names>S</given-names>
</name>
</person-group>. <article-title>Preoperative botulinum toxin and progressive pneumoperitoneum in loss of domain hernias&#x2014;our first 100 cases</article-title>. <source>Front Surg</source> (<year>2020</year>) <volume>7</volume>:<fpage>3</fpage>. <pub-id pub-id-type="doi">10.3389/fsurg.2020.00003</pub-id>
<pub-id pub-id-type="pmid">32181259</pub-id>
</mixed-citation>
</ref>
<ref id="B6">
<label>6.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Zamkowski</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Lerchuk</surname>
<given-names>O</given-names>
</name>
<name>
<surname>Porytsky</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Ushnevych</surname>
<given-names>Z</given-names>
</name>
<name>
<surname>Khomyak</surname>
<given-names>V</given-names>
</name>
<name>
<surname>&#x15a;mieta&#x144;ski</surname>
<given-names>M</given-names>
</name>
</person-group>. <article-title>The impact of botulinum toxin A application on reducing the necessity for &#x201c;Component Separation Techniques&#x201d; in giant incisional hernias: a dual-center, polish-ukrainian, retrospective cohort study</article-title>. <source>Pol Przegl Chir</source> (<year>2024</year>) <volume>96</volume>(<issue>6</issue>):<fpage>12</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.5604/01.3001.0054.4919</pub-id>
</mixed-citation>
</ref>
<ref id="B7">
<label>7.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Eucker</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Zerz</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Steinemann</surname>
<given-names>DC</given-names>
</name>
</person-group>. <article-title>Abdominal wall expanding system obviates the need for lateral release in giant incisional hernia and laparostoma</article-title>. <source>Surg Innov</source> (<year>2017</year>) <volume>24</volume>(<issue>5</issue>):<fpage>455</fpage>&#x2013;<lpage>61</lpage>. <pub-id pub-id-type="doi">10.1177/1553350617718065</pub-id>
<pub-id pub-id-type="pmid">28705101</pub-id>
</mixed-citation>
</ref>
<ref id="B8">
<label>8.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Niebuhr</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Aufenberg</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Dag</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Reinpold</surname>
<given-names>W</given-names>
</name>
<name>
<surname>Peiper</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Schardey</surname>
<given-names>HM</given-names>
</name>
<etal/>
</person-group> <article-title>Intraoperative Fascia tension as an alternative to component separation: a prospective observational study</article-title>. <source>Front Surg</source> (<year>2021</year>) <volume>7</volume>:<fpage>616669</fpage>. <pub-id pub-id-type="doi">10.3389/fsurg.2020.616669</pub-id>
</mixed-citation>
</ref>
<ref id="B9">
<label>9.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Niebuhr</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Malaibari</surname>
<given-names>ZO</given-names>
</name>
<name>
<surname>K&#xf6;ckerling</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Reinpold</surname>
<given-names>W</given-names>
</name>
<name>
<surname>Dag</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Eucker</surname>
<given-names>D</given-names>
</name>
<etal/>
</person-group> <article-title>Intraoperative fascial traction (IFT) for treatment of large ventral hernias: a retrospective analysis of 50 cases</article-title>. <source>Chirurg</source> (<year>2022</year>) <volume>93</volume>(<issue>3</issue>):<fpage>292</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1007/s00104-021-01552-0</pub-id>
</mixed-citation>
</ref>
<ref id="B10">
<label>10.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Niebuhr</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Wegner</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Dag</surname>
<given-names>H</given-names>
</name>
<name>
<surname>Reinpold</surname>
<given-names>W</given-names>
</name>
<name>
<surname>Woeste</surname>
<given-names>G</given-names>
</name>
<name>
<surname>K&#xf6;ckerling</surname>
<given-names>F</given-names>
</name>
</person-group>. <article-title>Preoperative botulinum toxin A (BTA) and intraoperative fascial traction (IFT) in the management of complex abdominal wall hernias</article-title>. <source>Hernia</source> (<year>2024</year>) <volume>28</volume>(<issue>6</issue>):<fpage>2273</fpage>&#x2013;<lpage>83</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-024-03156-z</pub-id>
</mixed-citation>
</ref>
<ref id="B11">
<label>11.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Muysoms</surname>
<given-names>FE</given-names>
</name>
<name>
<surname>Miserez</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Berrevoet</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Campanelli</surname>
<given-names>G</given-names>
</name>
<name>
<surname>Champault</surname>
<given-names>GG</given-names>
</name>
<name>
<surname>Chelala</surname>
<given-names>E</given-names>
</name>
<etal/>
</person-group> <article-title>Classification of primary and incisional abdominal wall hernias</article-title>. <source>Hernia</source> (<year>2009</year>) <volume>13</volume>(<issue>4</issue>):<fpage>407</fpage>&#x2013;<lpage>14</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-009-0518-x</pub-id>
<pub-id pub-id-type="pmid">19495920</pub-id>
</mixed-citation>
</ref>
<ref id="B12">
<label>12.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Paduraru</surname>
<given-names>DN</given-names>
</name>
<name>
<surname>Palcau</surname>
<given-names>AC</given-names>
</name>
<name>
<surname>Ion</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Seicaru</surname>
<given-names>R</given-names>
</name>
</person-group>. <article-title>Multimodal prehabilitation for hernia repair: linking metabolic modulation and mechanical methods</article-title>. <source>Biomedicines</source> (<year>2025</year>) <volume>13</volume>(<issue>12</issue>):<fpage>3117</fpage>. <pub-id pub-id-type="doi">10.3390/biomedicines13123117</pub-id>
</mixed-citation>
</ref>
<ref id="B13">
<label>13.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Tanaka</surname>
<given-names>EY</given-names>
</name>
<name>
<surname>Yoo</surname>
<given-names>JH</given-names>
</name>
<name>
<surname>Rodrigues</surname>
<given-names>AJ</given-names>
<suffix>Jr</suffix>
</name>
<name>
<surname>Utiyama</surname>
<given-names>EM</given-names>
</name>
<name>
<surname>Birolini</surname>
<given-names>D</given-names>
</name>
<name>
<surname>Rasslan</surname>
<given-names>S</given-names>
</name>
</person-group>. <article-title>A computerized tomography scan method for calculating the hernia sac and abdominal cavity volume in complex large incisional hernia with loss of domain</article-title>. <source>Hernia</source> (<year>2010</year>) <volume>14</volume>(<issue>1</issue>):<fpage>63</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-009-0560-8</pub-id>
<pub-id pub-id-type="pmid">19756913</pub-id>
</mixed-citation>
</ref>
<ref id="B14">
<label>14.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Sabbagh</surname>
<given-names>C</given-names>
</name>
<name>
<surname>Dumont</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Robert</surname>
<given-names>B</given-names>
</name>
<name>
<surname>Badaoui</surname>
<given-names>R</given-names>
</name>
<name>
<surname>Verhaeghe</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Regimbeau</surname>
<given-names>JM</given-names>
</name>
</person-group>. <article-title>Peritoneal volume is predictive of tension-free fascia closure of large incisional hernias with loss of domain: a prospective study</article-title>. <source>Hernia</source> (<year>2011</year>) <volume>15</volume>(<issue>5</issue>):<fpage>559</fpage>&#x2013;<lpage>65</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-011-0832-y</pub-id>
<pub-id pub-id-type="pmid">21584816</pub-id>
</mixed-citation>
</ref>
<ref id="B15">
<label>15.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>K&#xf6;hler</surname>
<given-names>G</given-names>
</name>
</person-group>. <article-title>Preoperative conditioning and surgical strategies for treatment of complex abdominal wall hernias</article-title>. <source>Chirurg</source> (<year>2020</year>) <volume>91</volume>(<issue>2</issue>):<fpage>134</fpage>&#x2013;<lpage>42</lpage>. <pub-id pub-id-type="doi">10.1007/s00104-019-01027-3</pub-id>
<pub-id pub-id-type="pmid">31471661</pub-id>
</mixed-citation>
</ref>
<ref id="B16">
<label>16.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Garc&#xED;a Ure&#xF1;a</surname>
<given-names>M&#xc1;</given-names>
</name>
<name>
<surname>L&#xf3;pez-Moncl&#xfa;s</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Bl&#xE1;zquez Hernando</surname>
<given-names>LA</given-names>
</name>
<name>
<surname>Mu&#xF1;oz-Rodriguez</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Roman Garc&#xED;a de Le&#xf3;n</surname>
<given-names>L</given-names>
</name>
<name>
<surname>Avil&#xE9;s Oliveros</surname>
<given-names>A</given-names>
</name>
<etal/>
</person-group> <article-title>Incisional hernia: open abdominal wall reconstruction. current state of the technique and results</article-title>. <source>Chirurgie (Heidelb)</source> (<year>2024</year>) <volume>95</volume>(<issue>1</issue>):<fpage>10</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1007/s00104-023-02005-6</pub-id>
</mixed-citation>
</ref>
<ref id="B17">
<label>17.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>De Luca</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Lopez-Monclus</surname>
<given-names>J</given-names>
</name>
<name>
<surname>Bl&#xe1;zquez Hernando</surname>
<given-names>LA</given-names>
</name>
<name>
<surname>Robin Valle de Lersundi</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Mu&#xf1;oz-Rodriguez</surname>
<given-names>JM</given-names>
</name>
<name>
<surname>Roman-Garcia de Le&#xf3;n</surname>
<given-names>L</given-names>
</name>
<etal/>
</person-group> <article-title>Cranial preperitoneal extension of the retromuscular repair in midline hernias: the Madrid rives technique</article-title>. <source>Am J Surg</source> (<year>2025</year>) <volume>250</volume>:<fpage>116626</fpage>. <pub-id pub-id-type="doi">10.1016/j.amjsurg.2025.116626</pub-id>
</mixed-citation>
</ref>
<ref id="B18">
<label>18.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Nip</surname>
<given-names>L</given-names>
</name>
<name>
<surname>Parker</surname>
<given-names>SG</given-names>
</name>
<name>
<surname>Scala</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Halligan</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Rockall</surname>
<given-names>TA</given-names>
</name>
<name>
<surname>Thomas</surname>
<given-names>R</given-names>
</name>
<etal/>
</person-group> <article-title>Essential anatomy for the abdominal wall surgeon: expert consensus of anatomical concepts and operative steps for posterior component separation</article-title>. <source>World J Surg</source> (<year>2025</year>) <volume>49</volume>(<issue>12</issue>):<fpage>3390</fpage>&#x2013;<lpage>401</lpage>. <pub-id pub-id-type="doi">10.1002/wjs.70155</pub-id>
</mixed-citation>
</ref>
<ref id="B19">
<label>19.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Timmer</surname>
<given-names>AS</given-names>
</name>
<name>
<surname>Claessen</surname>
<given-names>JJM</given-names>
</name>
<name>
<surname>Brouwer de Koning</surname>
<given-names>IM</given-names>
</name>
<name>
<surname>Haenen</surname>
<given-names>SM</given-names>
</name>
<name>
<surname>Belt</surname>
<given-names>EJT</given-names>
</name>
<name>
<surname>Bastiaansen</surname>
<given-names>AJNM</given-names>
</name>
<etal/>
</person-group> <article-title>Clinical outcomes of open abdominal wall reconstruction with the use of a polypropylene reinforced tissue matrix: a multicenter retrospective study</article-title>. <source>Hernia</source> (<year>2022</year>) <volume>26</volume>(<issue>5</issue>):<fpage>1241</fpage>&#x2013;<lpage>50</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-022-02604-y</pub-id>
</mixed-citation>
</ref>
<ref id="B20">
<label>20.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Fortelny</surname>
<given-names>RH</given-names>
</name>
<name>
<surname>Hofmann</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Baumann</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Riedl</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Kewer</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Hoelderle</surname>
<given-names>J</given-names>
</name>
<etal/>
</person-group> <article-title>Three-year follow-up analysis of the short-stitch <italic>versus</italic> long-stitch technique for elective midline abdominal closure randomized-controlled (ESTOIH) trial</article-title>. <source>Hernia</source> (<year>2024</year>) <volume>28</volume>(<issue>4</issue>):<fpage>1283</fpage>&#x2013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.1007/s10029-024-03025-9</pub-id>
</mixed-citation>
</ref>
<ref id="B21">
<label>21.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Fortelny</surname>
<given-names>RH</given-names>
</name>
<name>
<surname>Baumann</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Hofmann</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Riedl</surname>
<given-names>S</given-names>
</name>
<name>
<surname>Kewer</surname>
<given-names>JL</given-names>
</name>
<name>
<surname>Hoelderle</surname>
<given-names>J</given-names>
</name>
<etal/>
</person-group> <article-title>5-year clinical outcome of the ESTOIH trial comparing the short-bite <italic>versus</italic> large-bite technique for elective midline abdominal closure</article-title>. <source>Hernia</source> (<year>2025</year>) <volume>29</volume>(<issue>1</issue>):<fpage>263</fpage>. <pub-id pub-id-type="doi">10.1007/s10029-025-03459-9</pub-id>
</mixed-citation>
</ref>
<ref id="B22">
<label>22.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Golling</surname>
<given-names>M</given-names>
</name>
<name>
<surname>Baumann</surname>
<given-names>P</given-names>
</name>
<name>
<surname>Kuger</surname>
<given-names>F</given-names>
</name>
<name>
<surname>Fortelny</surname>
<given-names>RH</given-names>
</name>
</person-group>. <article-title>Impact of the SUture BIte TEchnique on clinical outcomes after midline laparotomy closure: SUBITE&#x2014;a systematic review and meta-analysis</article-title>. <source>Hernia</source> (<year>2026</year>) <volume>30</volume>(<issue>1</issue>):<fpage>221</fpage>. <pub-id pub-id-type="doi">10.1007/s10029-026-03700-z</pub-id>
</mixed-citation>
</ref>
<ref id="B23">
<label>23.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Mones</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Chobanova</surname>
<given-names>V</given-names>
</name>
<name>
<surname>Halama</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Nowroth</surname>
<given-names>T</given-names>
</name>
<name>
<surname>Pronadl</surname>
<given-names>M</given-names>
</name>
</person-group>. <article-title>Vertical mesh-mediated fascial traction and negative pressure wound therapy: a case series of nine patients in general and vascular surgery</article-title>. <source>Surg Technol Int</source> (<year>2024</year>) <volume>44</volume>:<fpage>131</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.52198/24.STI.44.HR1781</pub-id>
</mixed-citation>
</ref>
<ref id="B24">
<label>24.</label>
<mixed-citation publication-type="journal">
<person-group person-group-type="author">
<name>
<surname>Hees</surname>
<given-names>A</given-names>
</name>
<name>
<surname>Willeke</surname>
<given-names>F</given-names>
</name>
</person-group>. <article-title>Prevention of fascial retraction in the open abdomen with a novel device</article-title>. <source>Case Rep Surg</source> (<year>2020</year>) <volume>2020</volume>:<fpage>8254804</fpage>. <pub-id pub-id-type="doi">10.1155/2020/8254804</pub-id>
<pub-id pub-id-type="pmid">33145116</pub-id>
</mixed-citation>
</ref>
</ref-list>
</back>
</article>