AUTHOR=Suárez-Grau Juan Manuel , Navarro-Morales Laura , Tallon-Aguilar Luis , Morales-Conde Salvador , Padillo-Ruiz Francisco Javier TITLE=Closure of the Peritoneum in Laparoscopic Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP) With Cyanoacrylate Glue in a Microdroplet Device: A Single Surgeon Prospective Comparison vs. Barbed Suture JOURNAL=Journal of Abdominal Wall Surgery VOLUME=Volume 3 - 2024 YEAR=2024 URL=https://www.frontierspartnerships.org/journals/journal-of-abdominal-wall-surgery/articles/10.3389/jaws.2024.12562 DOI=10.3389/jaws.2024.12562 ISSN=2813-2092 ABSTRACT=To describe and compare a peritoneal closure technique using cyanoacrylate glue (Glubran 2® , GEM, Cardiolink SL) with a microdroplet device (Glutack® , GEM , Cardiolink SL) in laparoscopic transabdominal preperitoneal repair (TAPP) of inguinal hernia with the routinely used barbed suture peritoneal closure (V-Lock 3.0, Covidien France). Materials and methods: 60 patients undergoing TAPP repairfor uni- or bilateral inguinal hernia were randomized into one of two groups. One using as mesh fixation and peritoneal closure the Glutack® device with Glubran 2® cyanoacrylate glue (Glu-close group) and the other using mesh fixation with cyanoacrylate and peritoneal closure with V-lock 3.0 (Sut-close group), with a follow-up of 12 months. Demographic variables, operative time, peritoneal closure time, main surgical findings and main intra- and postoperative complications were analyzed prospectively. Results: 63 patients were included . The intraoperative complication rate was 0 for the glu-close group and 0 for the sut-close group, with no significant difference. The postoperative VAS score at the first and second check-up at 1 month and 3 months was 2.83 (SD 1.341) and 0.60 (SD 0.621) in the sut-close group and 1.03 (0.984) and 0.24 (SD 0.435) in the glue-close group, with significant differences (p<0.001 and p <0.012). Conclusion: The data demonstrated by the study are that the glue can be used safely to close the peritoneum with no complications.