AUTHOR=Huang Jie , Wang Mingshu , Cheng Anchun , Tian Bin , Ou Xuming , Wu Ying , Yang Qiao , Sun Di , Zhang Shaqiu , Mao Sai , Zhao Xinxin , Huang Juan , Gao Qun , Zhu Dekang , Jia Renyong , Chen Shun , Liu Mafeng 

TITLE=Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

JOURNAL=Acta Virologica

VOLUME=Volume 68 - 2024

YEAR=2024

URL=https://www.frontierspartnerships.org/journals/acta-virologica/articles/10.3389/av.2024.12023

DOI=10.3389/av.2024.12023

ISSN=1336-2305

ABSTRACT=Background: Duck enteritis virus (DEV) belongs to Alphaherpesvirinae, but little information is known about DEV UL7 gene and encoded protein. This study examined to describe molecular characterization of DEV pUL7 in vitro and determine whether DEV pUL7 was colocalization with pUL51.The results showed that UL7 gene could be regarded as a late gene.Moreover, immunofluorescence assay(IFA) revealed that pUL7 was observed around perinuclear cytoplasmic region, and pUL7 colocalization with pUL51 in the cytoplasm and nucleus via transfection into duck embryo fibroblast cells (DEFs).In conclusion, we identified the molecular characteristics of DEV UL7 gene，which is a late gene and its encoded protein colocalization with pUL51 in 2 transfected DEFs，our findings enriched the understanding of pUL7 and further research direction.