TY - JOUR AU - Bunnik, Eline M. AU - de Jongh, Dide AU - Massey, Emma PY - 2022 M3 - Meeting Report TI - Ethics of Early Clinical Trials of Bio-Artificial Organs JO - Transplant International UR - https://www.frontierspartnerships.org/articles/10.3389/ti.2022.10621 VL - 35 SN - 1432-2277 N2 - Regenerative medicine is the new frontier in the field of organ transplantation. Research groups around the world are using regenerative medicine technologies to develop bio-artificial organs for transplantation into human patients. While most of this research is still at the preclinical stage, bio-artificial organ technologies are gearing up for first-in-human clinical trials in the not-too-distant future. What are the ethical conditions under which early-phase clinical research of bio-artificial organs can be conducted safely and responsibly? What lessons can be learned from prior experiences with early-phase clinical trials in adjacent fields of research? This is a Meeting Report of an online international workshop organised in the context of the Horizon 2020-funded VANGUARD project, which is developing a bio-artificial pancreas for the treatment of patients with type 1 diabetes. ER -